HeLa cells were subjected to SDS PAGE followed by western blot with FNab04222(IL15RA antibody) at dilution of 1:500
Immunohistochemistry of paraffin-embedded human liver using FNab04222(IL15RA antibody) at dilution of 1:50
Background
High-affinity receptor for interleukin-15. Can signal both in cis and trans where IL15R from one subset of cells presents IL15 to neighboring IL2RG-expressing cells. Expression of different isoforms may alter or interfere with signal transduction. Isoform 5, isoform 6, isoform 7 and isoform 8 do not bind IL15. Signal transduction involves SYK.